Cytokine profiles in localized scleroderma and relationship to clinical features
نویسندگان
چکیده
منابع مشابه
Localized scleroderma: clinical spectrum and therapeutic update*
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tiss...
متن کاملLocalized Scleroderma
Morphea (localized scleroderma) is an autoimmune disease characterized by sclerosis of the skin and, in some cases, subcutaneous tissue. It occurs in children and adults. It is distinct from systemic sclerosis, but may nevertheless be associated with significant functional and cosmetic impairment. Morphea has several distinct subtypes, including circumscribed, linear, and generalized, all of wh...
متن کاملAge, sex and type distribution of localized Scleroderma in patients referred to Boo-Ali Hospital in Tehran, 1995-99
Background: There is no data on the characteristics of patients with localized scleroderma in Iran. Objective: In order to determine the age, sex and type distribution of localized scleroderma in Iran, this study was done on patients referred to Boo-Ali Hospital in Tehran in 1995-1999. Patients and Methods: This study was done as an existing data study on 39 patients with localized scleroderma ...
متن کاملTh1 and Th2 Cytokine Profiles in Malignant Pleural Effusion
Background: The alteration of Th1 and Th2 cytokine levels is the subject of controversy in pleural effusions caused by malignancy, a situation that favors a Th2 immune response. Objective: To examine the different levels of IL-4 and IL-10 (Th2 cytokines), and IL-2 and interferon-γ (IFN-γ) (Th1 cytokines) in malignant and non-malignant pleural effusions. Method: The cytokine levels in pleural fl...
متن کاملEsophageal Involvement in Scleroderma: Clinical, Endoscopic, and Manometric Features
Aim. To evaluate characteristics of esophageal involvement in scleroderma. Methods. The study was prospective and concerned 194 patients with a definite systemic sclerosis. Gastroesophageal endoscopy and esophageal manometry were performed in all the cases. Results. Symptoms were present in 118 cases (60.8%); they were signs of GERD or dysphagia, respectively, in 94 (48.4%) and 91 patients (46....
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ژورنال
عنوان ژورنال: Cytokine
سال: 2011
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2011.04.001